It is not supported on Windows Server 2019, Windows 11, or Windows Server 2022. Office 2010 is compatible with Windows XP SP3 32-bit, Windows Server 2003 SP2 32-bit, Windows Vista SP1-SP2, Windows Server 2008, Windows 7, Windows Server 2008 R2, Windows 8, Windows Server 2012, Windows 8.1, Windows Server 2012 R2, Windows 10 and Windows Server 2016. It is also the first version to require volume license product activation. Office 2010 is the first version of Office to ship in an 圆4 version. Office Mobile 2010, an update to Microsoft's mobile productivity suite was released on as a free upgrade from the Windows Phone Store for Windows Mobile 6.5 devices with a previous version of Office Mobile installed. A new Office Starter 2010 edition replaces Microsoft Works. It debuted Office Online, free Web-based versions of Excel, OneNote, PowerPoint, and Word. Collaborative editing features that enable multiple users to share and edit documents extended file format support integration with OneDrive and SharePoint and security improvements such as Protected View, a sandbox to protect users from malicious content are among its other new features. The ribbon introduced in Office 2007 for Access, Excel, Outlook, PowerPoint, and Word is the primary user interface for all applications in Office 2010 and is now customizable. Office 2010 introduces user interface enhancements including a Backstage view that consolidates document management tasks into a single location. The macOS equivalent, Microsoft Office 2011 for Mac was released on October 26, 2010.

Microsoft Office 2010 (codenamed Office 14 ) is a version of Microsoft Office for Microsoft Windows that was released to manufacturing on Ap and was later made available to retail on J as the successor to Office 2007 and the predecessor to Office 2013.

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